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OpenAI Agents SDK

Learning: 3/5 Production: 4/5
Languages: Python, JavaScript/TypeScript
License: MIT (Open Source)
Best For: General-purpose agents, prototyping
Community: 11,000+ GitHub stars

Key Features

  • Multi-Agent: Yes, via handoffs
  • Memory: Agent state management, session persistence
  • RAG: Yes, via function calling
  • Streaming: Yes, streaming support
  • MCP Support: Yes (official MCP support in 2025)
  • Human-in-Loop: Configurable checkpoints

Deployment

Cloud, Local, On-premise

Key Feature: Lightweight, provider-agnostic, official MCP support

LangChain/LangGraph

Learning: 4/5 Production: 5/5
Languages: Python, JavaScript/TypeScript
License: MIT (Open Source)
Best For: RAG, complex workflows, mature projects
Community: 34,000+ GitHub stars

Key Features

  • Multi-Agent: Yes, via subgraphs
  • Memory: Shared message history, context management
  • RAG: Excellent RAG support
  • Streaming: Yes, full streaming
  • MCP Support: Yes, MCP Adapters package
  • Human-in-Loop: Built-in human-in-loop nodes

Deployment

Cloud (LangSmith), Local

Key Feature: MCP Adapters, mature ecosystem, extensive integrations

CrewAI

Learning: 2/5 Production: 4/5
Languages: Python
License: MIT (Open Source)
Best For: Multi-agent teams, collaborative workflows
Community: 20,000+ GitHub stars

Key Features

  • Multi-Agent: Yes, role-based crews
  • Memory: Short-term, long-term, entity, contextual
  • RAG: Yes, via integrations
  • Streaming: Yes, streaming support
  • MCP Support: Partial (via tool framework)
  • Human-in-Loop: Yes, callback handlers

Deployment

Local, Cloud

Key Feature: 2-3x faster multi-agent orchestration, Flows for production

Claude Agent SDK

Learning: 2/5 Production: 5/5
Languages: Python, TypeScript/JavaScript
License: MIT (Open Source)
Best For: MCP-first development, Computer Use, Anthropic models
Community: 55,000+ stars (Claude Code)

Key Features

  • Multi-Agent: Yes, via subagents
  • Memory: Session persistence, MCP state
  • RAG: Yes, via MCP tools
  • Streaming: Yes, streaming support
  • MCP Support: Full native MCP support
  • Human-in-Loop: Fine-grained permissions

Deployment

Cloud, Local, On-premise

Key Feature: MCP-native, Computer Use, Agent Skills framework

LlamaIndex

Learning: 3/5 Production: 4/5
Languages: Python, TypeScript
License: MIT (Open Source)
Best For: Data-intensive RAG, document processing
Community: 47,100+ GitHub stars

Key Features

  • Multi-Agent: Yes, via Workflows 1.0
  • Memory: Retrieval-augmented context
  • RAG: Excellent, primary focus
  • Streaming: Yes, streaming support
  • MCP Support: Planned support
  • Human-in-Loop: Via Workflows

Deployment

Cloud (LlamaCloud), Local

Key Feature: Workflows 1.0, 300+ integrations, durable workflows

Quick Comparison

Framework Languages Learning Production License Multi-Agent MCP
OpenAI Agents SDK Python 3/5 4/5 MIT
LangChain/LangGraph Python 4/5 5/5 MIT
CrewAI Python 2/5 4/5 MIT
Claude Agent SDK Python 2/5 5/5 MIT
LlamaIndex Python 3/5 4/5 MIT

Keep Exploring

🌐 Ecosystem Map

20+ tools mapped by layer

💡 Use Cases

10 real-world implementations

📚 How AI Agents Work Course

8-module deep dive from zero to production